Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids

by Toh, Desiree-Faye Kaixin, Patil, Kiran M., Chen, Gang
Published 2017

G4-PROTAC: targeted degradation of a G-quadruplex binding protein

by Patil, Kiran M., Chin, Danielle, Seah, Hui Ling, Shi, Qi, Lim, Kah Wai, Phan, Anh Tuân
Published 2022

Incorporating a guanidine-modified cytosine base into triplex-forming PNAs for the recognition of a C-G pyrimidine–purine inversion site of an RNA duplex

by Toh, Desiree-Faye Kaixin, Devi, Gitali, Patil, Kiran M., Qu, Qiuyu, Maraswami, Manikantha, Xiao, Yunyun, Loh, Teck Peng, Zhao, Yanli, Chen, Gang
Published 2017

RNA secondary structure-based design of antisense peptide nucleic acids for modulating disease-associated aberrant tau pre-mRNA alternative splicing

by Ong, Alan Ann Lerk, Tan, Jiazi, Bhadra, Malini, Dezanet, Clément, Patil, Kiran M., Chong, Mei Sian, Kierzek, Ryszard, Decout, Jean-Luc, Roca, Xavier, Chen, Gang
Published 2019

Incorporating uracil and 5-halouracils into short peptide nucleic acids for enhanced recognition of A–U pairs in dsRNAs

by Patil, Kiran M., Ong, Alan Ann Lerk, Krishna, Manchugondanahalli Shivakumar, Toh, Desiree-Faye Kaixin, Yuan, Zhen, Meng, Zhenyu, Shu, Zhiyu, Zhang, Haiping, Lu, Lanyuan, Lu, Yunpeng, Chen, Gang
Published 2019

General recognition of U‑G, U‑A, and C‑G pairs by double-stranded RNA-binding PNAs incorporated with an artificial nucleobase

by Ong, Alan Ann Lerk, Toh, Desiree-Faye Kaixin, Patil, Kiran M., Meng, Zhenyu, Yuan, Zhen, Krishna, Manchugondanahalli S., Devi, Gitali, Haruehanroengra, Phensinee, Lu, Yunpeng, Xia, Kelin, Okamura, Katsutomo, Sheng, Jia, Chen, Gang
Published 2021

A short chemically modified dsRNA-Binding PNA (dbPNA) inhibits influenza viral replication by targeting viral RNA panhandle structure

by Kesy, Julita, Patil, Kiran M., Kumar, Subaschandrabose Rajesh, Shu, Zhiyu, Yong, Hui Yee, Zimmermann, Louis, Ong, Alan Ann Lerk, Toh, Desiree-Faye Kaixin, Krishna, Manchugondanahalli S., Yang, Lixia, Decout, Jean-Luc, Luo, Dahai, Prabakaran, Mookkan, Chen, Gang, Kierzek, Elzbieta
Published 2021

Recognition of RNA secondary structures with a programmable peptide nucleic acid-based platform

by Lu, Rongguang, Deng, Liping, Lian, Yun, Ke, Xin, Yang, Lixia, Xi, Kun, Ong, Alan Ann Lerk, Chen, Yanyu, Zhou, Hanting, Meng, Zhenyu, Lin, Ruiyu, Fan, Shijian, Liu, Yining, Toh, Desiree-Faye Kaixin, Zhan, Xuan, Krishna, Manchugondanahalli S., Patil, Kiran M., Lu, Yunpeng, Liu, Zheng, Zhu, Lizhe, Wang, Hongwei, Li, Guobao, Chen, Gang
Published 2024

Targeting RNA Editing of Antizyme Inhibitor 1: a Potential Oligonucleotide-Based Antisense Therapy for Cancer.

by Tai Tay, Daryl Jin, Song, Yangyang, Peng, Boya, Toh, Tan Boon, Hooi, Lissa, Kaixin Toh, Desiree-Faye, Hong, HuiQi, Tang, Sze Jing, Han, Jian, Gan, Wei Liang, Man Chan, Tim Hon, Krishna, Manchugondanahalli S, Patil, Kiran M, Maraswami, Manikantha, Loh, Teck Peng, Dan, Yock Young, Zhou, Lei, Bonney, Glenn Kunnath, Kah-Hoe Chow, Pierce, Chen, Gang, Kai-Hua Chow, Edward, Le, Minh Tn, Chen, Leilei
Published 2021