An antimicrobial helix A-derived peptide of heparin cofactor II blocks endotoxin responses in vivo

Host defense peptides are key components of the innate immune system, providing multi-facetted responses to invading pathogens. Here, we describe that the peptide GKS26 (GKSRIQRLNILNAKFAFNLYRVLKDQ), corresponding to the A domain of heparin cofactor II (HCII), ameliorates experimental septic shock. T...

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Main Authors: Papareddy, Praveen, Kalle, Martina, Morgelin, Matthias, Schmidtchen, Artur, Malmsten, Martin, Singh, Shalini
其他作者: Lee Kong Chian School of Medicine (LKCMedicine)
格式: Article
語言:English
出版: 2014
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在線閱讀:https://hdl.handle.net/10356/103671
http://hdl.handle.net/10220/19290
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