A minimal sequence for left‐handed G‐quadruplex formation

Recently, we observed the first example of a left‐handed G‐quadruplex structure formed by natural DNA, named Z‐G4 . We analysed the Z‐G4 structure and inspected its primary 28‐nt sequence in order to identify motifs that convey the unique left‐handed twist. Using circular dichroism spectroscopy, NMR...

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Bibliographic Details
Main Authors: Bakalar, Blaž, Heddi, Brahim, Schmitt, Emmanuelle, Mechulam, Yves, Phan, Anh Tuân
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2020
Subjects:
DNA
Online Access:https://hdl.handle.net/10356/140140
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Institution: Nanyang Technological University
Language: English

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