Iterative addition of carbon nucleophiles toN,N-dialkyl carboxamides for synthesis of α-tertiary amines

Iterative addition of carbon nucleophiles toN,N-dialkyl carboxamides for synthesis of α-tertiary amines

A protocol for the synthesis of α-tertiary amines was developed by iterative addition of carbon nucleophiles toN,N-dialkyl carboxamides. Nucleophilic 1,2-addition of organolithium reagents to carboxamides forms anionic tetrahedral carbinolamine (hemiaminal) intermediates, which are subsequently trea...

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書目詳細資料
Main Authors:	Chen, Jiahua, Lim, Jun Wei, Ong, Derek Yiren, Chiba, Shunsuke
其他作者:	School of Physical and Mathematical Sciences
格式:	Article
語言:	English
出版:	2022
主題:	Science::Chemistry Carbon Nucleophiles
在線閱讀:	https://hdl.handle.net/10356/154825
標簽:	添加標簽沒有標簽, 成為第一個標記此記錄!

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