Understanding artemisinin compounds mode of action in killing Plasmodium falciparum by using mass spectrometry cellular thermal shift assay
Plasmodium falciparum (Pf) is a lethal cause of malaria, which is a global health burden with an estimated 627 thousand deaths during 2020. Dihydroartemisinin (DHA)-piperaquine is one form of artemisinin-combination therapies (ACTs) used as a first-line antimalarial drug. Previous studies show...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2023
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| Online Access: | https://hdl.handle.net/10356/170075 |
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| Institution: | Nanyang Technological University |
| Language: | English |