Study of islet amyloid polypeptide aggregation and its inhibition mechanisms.
Islet amyloid polypeptide (IAPP), a 37-amino acid polypeptide hormone of calcitonin family, is co-expressed and co-secreted with insulin in pancreatic islet β cells. Abnormal aggregation of islet amyloid polypeptide (IAPP) into amyloid fibrils is a hallmark of type 2 diabetes. Determining the molec...
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Main Author: | Wei, Lei. |
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Other Authors: | Konstantin Pervushin |
Format: | Theses and Dissertations |
Language: | English |
Published: |
2011
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Subjects: | |
Online Access: | http://hdl.handle.net/10356/42907 |
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Institution: | Nanyang Technological University |
Language: | English |
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