Selective binding to mRNA duplex regions by chemically modified PNAs stimulates ribosomal frameshifting
Minus-one programmed ribosomal frameshifting (-1 PRF) is a prominent mechanism that exists in ribonucleic acid (RNA) viruses. It allows precise maintenance of ratio between viral structural and enzymatic proteins, and is involved in the regulation of the half-life of cellular messenger ribonucleic a...
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| Format: | Theses and Dissertations |
| Language: | English |
| Published: |
2018
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| Online Access: | http://hdl.handle.net/10356/73165 |
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| Institution: | Nanyang Technological University |
| Language: | English |