Monitoring chaperone aggregation to measure ribosomal stalling
Proteostatic disequilibrium, the inability for cellular components to synchronously balance protein synthesis, folding and degradation, has been implicated in various ageing-related diseases, including Alzheimer’s and Parkinson’s disease, which often manifest through protein aggregation, toxicity an...
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| Format: | Final Year Project |
| Language: | English |
| Published: |
2019
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| Online Access: | http://hdl.handle.net/10356/78994 |
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| Institution: | Nanyang Technological University |
| Language: | English |