Aza-bridged bisphenanthrolinyl Pt(ii) complexes : efficient stabilization and topological selectivity on telomeric G-quadruplexes
Two platinum complexes with an aza-bridged bis(1,10-phenanthrolin-2-yl)amine (bpa) were synthesized. The two phenanthrolines in bpa entered a flat plane prior to binding of nucleic acids, which bestowed on the two Pt complexes a significantly high stabilizing ability on both DNA and RNA G-quadruplex...
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| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2018
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/89489 http://hdl.handle.net/10220/44940 |
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| Institution: | Nanyang Technological University |
| Language: | English |