Interferon-inducible IFI16, a negative regulator of cell growth, down-regulates expression of human telomerase reverse transcriptase (hTERT) gene

• Main Authors: Song L.L., Ponomareva L., Shen H., Duan X., Alimirah F., Choubey D.
• Other Authors: MICROBIOLOGY AND IMMUNOLOGY
• Format: Article
• Published: 2019
• Subjects: antimitotic agent; aphidicolin; cgk 1026; interferon; interferon inducible IFI16 protein; luciferase; messenger RNA; Myc protein; protein; telomerase; telomerase reverse transcriptase; unclassified drug; IFI16 protein, human; nuclear protein; phosphoprotein; TERT protein, human; article; cell cycle progression; cell growth; cell interaction; cell stimulation; controlled study; diploidy; enzyme activity; fibroblast; gene expression regulation; gene overexpression; growth inhibition; HeLa cell; human; human cell; immunoblotting; real time polymerase chain reaction; receptor down regulation; reporter gene; signal transduction; steady state; telomeric repeat amplification protocol; transcription regulation; cell division; cell line; down regulation; gene silencing; genetic transcription; genetics; metabolism; oncogene myc; physiology; Cell Division; Cell Line; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Knockdown Techniques; Genes, myc; Hela Cells; Humans; Nuclear Proteins; Phosphoproteins; RNA, Messenger; Telomerase; Transcription, Genetic
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161822
• Institution: National University of Singapore

10.1371/journal.pone.0008569