Binding specificity of polypeptide substrates in NS2B/NS3pro serine protease of dengue virus type 2: A molecular dynamics Study

Binding specificity of polypeptide substrates in NS2B/NS3pro serine protease of dengue virus type 2: A molecular dynamics Study

© 2015 Elsevier Inc. All rights reserved. The pathogenic dengue virus (DV) is a growing global threat, particularly in South East Asia, for which there is no specific treatment available. The virus possesses a two-component (NS2B/NS3) serine protease that cleaves the viral precursor proteins. Here,...

Saved in:

書目詳細資料
Main Authors:	Pathumwadee Yotmanee, Thanyada Rungrotmongkol, Kanin Wichapong, Sy Bing Choi, Habibah A. Wahab, Nawee Kungwan, Supot Hannongbua
格式:	雜誌
出版:	2018
主題:	Chemistry Computer Science Materials Science
在線閱讀:	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84935917965&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/54289
標簽:	添加標簽沒有標簽, 成為第一個標記此記錄!

相似書籍

Binding specificity of polypeptide substrates in NS2B/NS3pro serine protease of dengue virus type 2: A molecular dynamics Study
由: Pathumwadee Yotmanee, et al.
出版: (2018)

Computer-based methods for analyzing inhibitors of dengue virus NS2B/NS3 protease and of Wee1 kinase
由: Kanin Wichapong
出版: (2009)

Effect of D168V mutation in NS3/4A HCV protease on susceptibilities of faldaprevir and danoprevir
由: Arthitaya Meeprasert, et al.
出版: (2018)

Steady-state cleavage kinetics for dengue virus type 2 NS2B-NS3(pro) serine protease with synthetic peptides
由: Rabuesak Khumthong, et al.
出版: (2018)

The Two-Component Protease NS2B-NS3 of Dengue Virus Type 2: Cloning, Expression in Escherichia coli and Purification of the NS2B, NS3(pro) and NS2B-NS3 Proteins
由: Veerawat Champreda, et al.
出版: (2018)

Reaction mechanisms of substrate and inhibitor with ns2b/ns3 serine protease of zika virus by mm and qm/mm simulations
由: Bodee Nutho
出版: (2018)

Effect of D168V mutation in NS3/4A HCV protease on susceptibilities of faldaprevir and danoprevir
由: Meeprasert A., et al.
出版: (2017)

Biochemical characterisation of NS2B-NS3 protease from flaviviruses
由: Nah, Jojo Qian Hui
出版: (2016)

Structures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitors
由: Phoo, Wint Wint, et al.
出版: (2019)

Competitive inhibition of the dengue virus NS3 serine protease by synthetic peptides representing polyprotein cleavage sites
由: Santad Chanprapaph, et al.
出版: (2018)

A comparative biochemical analysis of the NS2B(H)-NS3pro protease complex from four dengue virus serotypes
由: Tawin Iempridee, et al.
出版: (2018)

Enzymatic analysis of recombinant Japanese encephalitis virus NS2B(H)-NS3pro protease with fluorogenic model peptide substrates
由: Muhammad Junaid, et al.
出版: (2018)

Enzymatic analysis of recombinant Japanese encephalitis virus NS2B(H)-NS3pro protease with fluorogenic model peptide substrates
由: Muhammad Junaid, et al.
出版: (2015)

Allosteric Inhibitors of Zika Virus NS2B-NS3 Protease Targeting Protease in "Super-Open" Conformation
由: Meewan I.
出版: (2023)

Crystal structure of unlinked NS2B-NS3 protease from Zika virus
由: Zhang, Zhenzhen, et al.
出版: (2017)

Design, synthesis and biological evaluation of inhibitors of flavivirus NS2B/NS3 protease
由: GAO YAOJUN
出版: (2010)

Tripeptide inhibitors of dengue and West Nile virus NS2B-NS3 protease
由: Schüller, A., et al.
出版: (2014)

INVESTIGATING THE ROLE OF NS2B DYNAMICS IN DENGUE VIRUS NS3 PROTEASE FUNCTION
由: LEE WEN HAO KENNETH
出版: (2021)

A straightforward experimental approach to expression, purification, refolding, and enzymatic analysis of recombinant dengue virus NS2B(H)-NS3pro protease
由: M. Junaid, et al.
出版: (2018)

Low susceptibility of asunaprevir towards R155K and D168A point mutations in HCV NS3/4A protease: A molecular dynamics simulation
由: Jirayu Kammarabutr, et al.
出版: (2019)

Probing the substrate specificity of the dengue virus type 2 NS3 serine protease by using internally quenched fluorescent peptides
由: Pornwaratt Niyomrattanakit, et al.
出版: (2018)

The flavivirus NS2B–NS3 protease–helicase as a target for antiviral drug development
由: Luo, Dahai, et al.
出版: (2016)

Structure of the NS2B-NS3 protease from Zika virus after self-cleavage
由: Phoo, Wint Wint, et al.
出版: (2017)

Analysis of cellular proteome changes in response to ZIKV NS2B-NS3 protease expression
由: Chontida Tangsongcharoen, et al.
出版: (2020)

Structure of the NS2B-NS3 protease from Zika virus after self-cleavage
由: Phoo, W.W, et al.
出版: (2020)

Dynamic interactions of post cleaved NS2B cofactor and NS3 protease identified by integrative structural approaches
由: Quek, Jun-Ping, et al.
出版: (2022)

Identification of residues in the dengue virus type 2 NS2B cofactor that are critical for NS3 protease activation
由: Pornwaratt Niyomrattanakit, et al.
出版: (2018)

Development of an in vitro assay system for the analysis of dengue virus type 2 NS2B-NS3 protease
由: Rabuesak Khumthong
出版: (2023)

Dengue protease activity: The structural integrity and interaction of NS2B with NS3 protease and its potential as a drug target
由: Phong, W.Y., et al.
出版: (2014)

NMR analysis of the dynamic exchange of the NS2B cofactor between open and closed conformations of the West Nile virus NS2B-NS3 protease
由: Su, X.-C., et al.
出版: (2014)

Drug discovery targeting NS2B-NS3 proteases from dengue and Zika viruses - II
由: Chan, Kwok Fong
出版: (2017)

Inhibition of the NS2B-NS3 protease - Towards a causative therapy for dengue virus diseases
由: Gerd Katzenmeier
出版: (2018)

Exploring the binding of peptidic West Nile virus NS2B-NS3 protease inhibitors by NMR
由: Kang, C., et al.
出版: (2014)

In vitro determination of dengue virus type 2 NS2B-NS3 protease activity with fluorescent peptide substrates
由: Rabuesak Khumthong, et al.
出版: (2018)

Structural insights into the inhibition of Zika virus NS2B-NS3 protease by a small-molecule inhibitor
由: Li, Yan, et al.
出版: (2020)

Identification and structural characterization of small molecule fragments targeting Zika virus NS2B-NS3 protease
由: Quek, Jun Ping, et al.
出版: (2020)

Structural platform for the autolytic activity of an intact NS2B-NS3 protease complex from dengue virus
由: Opas Choksupmanee, et al.
出版: (2018)

SYNTHESIS AND BIOLOGICAL EVALUATION OF SMALL MOLECULES AS INHIBITORS OF WEST NILE VIRUS NS2B-NS3 PROTEASE
由: SANJAY SAMANTA
出版: (2013)

Full length and protease domain activity of chikungunya virus nsP2 differ from other alphavirus nsP2 proteases in recognition of small peptide substrates
由: Chonticha Saisawang, et al.
出版: (2018)

Glutathionylation of chikungunya nsP2 protein affects protease activity
由: Chonticha Saisawang, et al.
出版: (2018)