Efficacy and day 7 plasma piperaquine concentrations in African children treated for uncomplicated malaria with dihydroartemisinin-piperaquine
Background: One promising new Artemisinin-based combination therapies (ACTs) is dihydroartemisinin-piperaquine (DHA-PQ). However, the pharmacokinetics of piperaquine and the relationship between drug levels and clinical efficacy are incompletely characterized, particularly in children. Methods: We p...
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Main Authors: | Issaka Zongo, Fabrice A. Somé, Serge A.M. Somda, Sunil Parikh, Noel Rouamba, Philip J. Rosenthal, Joel Tarning, Niklas Lindegardh, François Nosten, Jean Bosco Ouédraogo |
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Other Authors: | Bobo-Dioulasso |
Format: | Article |
Published: |
2018
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/32995 |
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Institution: | Mahidol University |
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