The thrombin-derived host defense peptide GKY25 inhibits endotoxin-induced responses through Interactions with lipopolysaccharide and macrophages/monocytes
Host defense peptides have recently gained much interest as novel anti-infectives owing to their ability to kill bacteria and simultaneously modulate host cell responses. The cationic host defense peptide GKY25 (GKYGFYTHVFRLKKWIQKVIDQFGE), derived from the C terminus of human thrombin, inhibits proi...
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Main Authors: | Schmidtchen, Artur, Morgelin, Matthias, Hansen, Finja C., Kalle-Brune, Martina, van der Plas, Mariena J. A., Strömdahl, Ann-Charlotte, Malmsten, Martin |
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其他作者: | Lee Kong Chian School of Medicine (LKCMedicine) |
格式: | Article |
語言: | English |
出版: |
2015
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在線閱讀: | https://hdl.handle.net/10356/103339 http://hdl.handle.net/10220/25772 |
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機構: | Nanyang Technological University |
語言: | English |
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