Synthesis of (−)-deoxynupharidine by allenic hydroxylamine cyclisation
(−)-Deoxynupharidine has been synthesised via an intermediate that can also be used for other Nuphar alkaloids. Significant steps include the optimised enzymatic resolution of an allenic alcohol, highly diastereoselective silver-catalysed cyclisation of an allenic hydroxylamine, selective cross-meta...
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Main Authors: | Bates, Roderick Wayland, Lim, Chia Juan, Collier, Steven J., Sukumaran, Joly |
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Other Authors: | School of Physical and Mathematical Sciences |
Format: | Article |
Language: | English |
Published: |
2015
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/103835 http://hdl.handle.net/10220/25855 |
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Institution: | Nanyang Technological University |
Language: | English |
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