Synergistic antibacterial efficacy of early combination treatment with tobramycin and quorum-sensing inhibitors against Pseudomonas aeruginosa in an intraperitoneal foreign-body infection mouse model
Objectives:Quorum sensing (QS)-deficient Pseudomonas aeruginosa biofilms formed in vitro are more susceptible to tobramycin than QS-proficient P. aeruginosa biofilms, and combination treatment with a QS inhibitor (QSI) and tobramycin shows synergistic effects on the killing of in vitro biofilms. We...
محفوظ في:
المؤلفون الرئيسيون: | Jakobsen, Tim H., Christensen, Louise Dahl, Gennip, Maria van, Alhede, Morten, Hougen, Hans Petter, Høiby, Niels, Bjarnsholt, Thomas, Givskov, Michael |
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التنسيق: | مقال |
اللغة: | English |
منشور في: |
2013
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الموضوعات: | |
الوصول للمادة أونلاين: | https://hdl.handle.net/10356/104841 http://hdl.handle.net/10220/17023 |
الوسوم: |
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