Structural basis for PTPA interaction with the invariant C-terminal tail of PP2A

Protein phosphatase 2A (PP2A) is a highly abundant heterotrimeric Ser/Thr phosphatase involved in the regulation of a variety of signaling pathways. The PP2A phosphatase activator (PTPA) is an ATP-dependent activation chaperone, which plays a key role in the biogenesis of active PP2A. The C-terminal...

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Bibliographic Details
Main Authors: Löw, Christian, Quistgaard, Esben M., Kovermann, Michael, Anandapadamanaban, Madhanagopal, Balbach, Jochen, Nordlund, Pär
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2015
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Online Access:https://hdl.handle.net/10356/106914
http://hdl.handle.net/10220/25197
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Institution: Nanyang Technological University
Language: English

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