Structural basis for PTPA interaction with the invariant C-terminal tail of PP2A
Protein phosphatase 2A (PP2A) is a highly abundant heterotrimeric Ser/Thr phosphatase involved in the regulation of a variety of signaling pathways. The PP2A phosphatase activator (PTPA) is an ATP-dependent activation chaperone, which plays a key role in the biogenesis of active PP2A. The C-terminal...
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Main Authors: | Löw, Christian, Quistgaard, Esben M., Kovermann, Michael, Anandapadamanaban, Madhanagopal, Balbach, Jochen, Nordlund, Pär |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2015
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/106914 http://hdl.handle.net/10220/25197 |
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Institution: | Nanyang Technological University |
Language: | English |
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