Carbene-catalyzed α,γ-deuteration of enals under oxidative conditions

Carbene-catalyzed α,γ-deuteration of enals under oxidative conditions

Organic compounds with deuterated allyl groups are very attractive for drug entities to enhance pharmacokinetic properties, since allylic C-H bonds are prone to metabolic oxidation and the deuterated versions can be less prone to such metabolism. However, direct deuteration at allylic C-H moieties i...

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書目詳細資料
Main Authors:	Zhang, Xiaolei, Chen, Qiao, Song, Runjiang, Xu, Jun, Tian, Weiyi, Li, Shaoyuan, Jin, Zhichao, Chi, Robin Yonggui
其他作者:	School of Physical and Mathematical Sciences
格式:	Article
語言:	English
出版:	2021
主題:	Science::Chemistry Carbene Catalysis Allyl Group
在線閱讀:	https://hdl.handle.net/10356/148639
標簽:	添加標簽沒有標簽, 成為第一個標記此記錄!
機構:	Nanyang Technological University
語言:	English

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