Cell-free DNA promotes thrombin autolysis and generation of thrombin-derived C-terminal fragments
Cell-free DNA (cfDNA) is the major structural component of neutrophil extracellular traps (NETs), an innate immune response to infection. Antimicrobial proteins and peptides bound to cfDNA play a critical role in the bactericidal property of NETs. Recent studies have shown that NETs have procoagulan...
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Main Authors: | Saravanan, Rathi, Choong, Yeu Khai, Lim, Chun Hwee, Lim, Li Ming, Petrlova, Jitka, Schmidtchen, Artur |
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Other Authors: | Lee Kong Chian School of Medicine (LKCMedicine) |
Format: | Article |
Language: | English |
Published: |
2021
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/152056 |
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Institution: | Nanyang Technological University |
Language: | English |
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