Atomic insights of an up and down conformation of the Acinetobacter baumannii F₁-ATPase subunit ε and deciphering the residues critical for ATP hydrolysis inhibition and ATP synthesis
The Acinetobacter baumannii F1 FO -ATP synthase (α3 :β3 :γ:δ:ε:a:b2 :c10 ), which is essential for this strictly respiratory opportunistic human pathogen, is incapable of ATP-driven proton translocation due to its latent ATPase activity. Here, we generated and purified the first recombinant A. bauma...
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Main Authors: | Saw, Wuan Geok, Le, Khoa Cong Minh, Shin, Joon, Kwek, Jes Hui Min, Wong, Chui Fann, Ragunathan, Priya, Fong, Tuck Choy, Müller, Volker, Grüber, Gerhard |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2023
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/170125 |
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Institution: | Nanyang Technological University |
Language: | English |
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