Yb(OTf)3-catalyzed allenation/ cycloisomerization reaction with propargylic alcohols and amides : a facile synthetic approach to oxazole and its derivatives.
An efficient method for allenation/cycloisomerization reaction of propargylic alcohols with amides in the presence of Yb(OTf)3 (5 mol %) at 100oC to afford oxazoles in moderate to excellent yields is reported herein. The method features ease of starting material preparation, use of a low cost and...
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| Format: | Final Year Project |
| Language: | English |
| Published: |
2010
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| Online Access: | http://hdl.handle.net/10356/39686 |
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| Institution: | Nanyang Technological University |
| Language: | English |