In vitro reconstitution of telomeric mono-nucleosomes
Reconstitution of telomeric DNA (telo-DNA) with human histone octamer, to form telomeric nucleosomes, was often quoted as challenging given that telo-DNA does not possess a positioning sequence and is out-of-sync with the helical periodicity of DNA. In this report, I endeavor to demonstrate telomeri...
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| Format: | Final Year Project |
| Language: | English |
| Published: |
2016
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| Online Access: | http://hdl.handle.net/10356/67347 |
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| Institution: | Nanyang Technological University |
| Language: | English |