Angiopoietin-like 4 Mediates Colonic Inflammation by Regulating Chemokine Transcript Stability via Tristetraprolin

• Main Authors: Phua, Terri, Sng, Ming Keat, Tan, Eddie Han Pin, Chee, Dickson Shao Liang, Li, Yinliang, Wee, Jonathan Wei Kiat, Teo, Ziqiang, Chan, Jeremy Soon Kiat, Lim, Maegan Miang Kee, Tan, Chek Kun, Zhu, Pengcheng, Arulampalam, Velmurugesan, Tan, Nguan Soon
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2017
• Subjects: Acute inflammation; Physiology
• Online Access: https://hdl.handle.net/10356/83483; http://hdl.handle.net/10220/42647
• Institution: Nanyang Technological University

Many gastrointestinal diseases exhibit a protracted and aggravated inflammatory response that can lead to hypercytokinaemia, culminating in extensive tissue damage. Recently, angiopoietin-like 4 (ANGPTL4) has been implicated in many inflammation-associated diseases. However, how ANGPTL4 regulates co...