Iron-catalyzed directed C2-alkylation and alkenylation of indole with vinylarenes and alkynes
An iron–N-heterocyclic carbene catalyst generated from an iron(III) salt, an imidazolinium salt, and a Grignard reagent promotes alkylation and alkenylation reactions at the indole C2-position with vinylarenes and internal alkynes, respectively, via imine-directed C–H activation. The former reaction...
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Main Authors: | Yamakawa, Takeshi, Yoshikai, Naohiko, Wong, Mun Yee |
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Other Authors: | School of Physical and Mathematical Sciences |
Format: | Article |
Language: | English |
Published: |
2015
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/107215 http://hdl.handle.net/10220/25309 |
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Institution: | Nanyang Technological University |
Language: | English |
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