Structural insights into the inhibition of Zika virus NS2B-NS3 protease by a small-molecule inhibitor
Zika virus (ZIKV) infection has become a global public health concern. The viral NS2B-NS3 protease is an attractive antiviral target because of its role in maturation of viral non-structural proteins. Substrate-derived protease inhibitors have been investigated, but it remains challenging to develop...
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Main Authors: | Li, Yan, Zhang, Zhenzhen, Phoo, Wint Wint, Loh, Ying Ru, Li, Rong, Yang, Hai Yan, Jansson, Anna E., Hill, Jeffrey, Keller, Thomas H., Nacro, Kassoum, Luo, Dahai, Kang, CongBao |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2020
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/140349 |
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Institution: | Nanyang Technological University |
Language: | English |
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