Carbene-catalyzed dynamic kinetic resolution for asymmetric access to phthalidyl esters and benzofuranone derivatives
In this thesis, we have demonstrated two dynamic kinetic resolution strategies enabled by N-heterocyclic carbene. Firstly, asymmetric acylation of hydroxyphthalides through N-heterocyclic carbene catalyzed dynamic kinetic resolution approach has been achieved. In addition, enantioselective modificat...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2020
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| Online Access: | https://hdl.handle.net/10356/142580 |
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| Institution: | Nanyang Technological University |
| Language: | English |