λ-integrase mediated seamless vector transgenesis platform
Genome engineering is an important component of gene/cell therapy and molecular medicine. In this respect, several DNA editing tools, such as ZFNs, TALEN and CRISPR-Cas system are being currently used for transgenesis. However, issues like insertional mutagenesis, off-target events, and small payloa...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2020
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| Online Access: | https://hdl.handle.net/10356/142767 |
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| Institution: | Nanyang Technological University |
| Language: | English |