A reaction mode of carbene-catalysed aryl aldehyde activation and induced phenol OH functionalization

• Main Authors: Chen, Xingkuan, Wang, Hongling, Doitomi, Kazuki, Ooi, Chong Yih, Zheng, Pengcheng, Liu, Wangsheng, Guo, Hao, Yang, Song, Song, Bao-An, Hirao, Hajime, Chi, Yonggui Robin
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2018
• Subjects: Carbene; Aldehyde
• Online Access: https://hdl.handle.net/10356/87071; http://hdl.handle.net/10220/44271
• Institution: Nanyang Technological University

The research in the field of asymmetric carbene organic catalysis has primarily focused on the activation of carbon atoms in non-aromatic scaffolds. Here we report a reaction mode of carbene catalysis that allows for aromatic aldehyde activation and remote oxygen atom functionalization. The addition...