Luteolin escape mutants of dengue virus map to prM and NS2B and reveal viral plasticity during maturation
We previously showed that luteolin, a well-known plant-derived component found in the “heat clearing” class of Traditional Chinese Medicine (TCM) herbs, is an uncompetitive inhibitor (Ki 58.6 μM) of the host proprotein convertase furin, an endoprotease that is required for maturation of flaviviruses...
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| Main Authors: | , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/90097 http://hdl.handle.net/10220/48386 |
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| Institution: | Nanyang Technological University |
| Language: | English |