Design and examine oligonucleotide structures as inhibitors to topoisomerase IV
Topoisomerase IV is an enzyme that exclusively presents in prokaryotic cells and is mainly responsible for unwinding interlocked DNA strands at the final stage of prokaryotic replication. Since it is a prokaryotic enzyme, various types of quinolones were developed in the past as inhibitors of topo I...
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| Format: | Theses and Dissertations |
| Language: | English |
| Published: |
2014
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| Online Access: | http://hdl.handle.net/10356/61861 |
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| Institution: | Nanyang Technological University |
| Language: | English |