Anti-endotoxic and antibacterial effects of a dermal substitute coated with host defense peptides
Biomaterials used during surgery and wound treatment are of increasing importance in modern medical care. In the present study we set out to evaluate the addition of thrombin-derived host defense peptides to human acellular dermis (hAD, i.e. epiflex®). Antimicrobial activity of the functionalized hA...
Saved in:
Main Authors: | Kasetty, Gopinath, Kalle, Martina, Mörgelin, Matthias, Brune, Jan C., Schmidtchen, Artur |
---|---|
Other Authors: | Lee Kong Chian School of Medicine (LKCMedicine) |
Format: | Article |
Language: | English |
Published: |
2015
|
Online Access: | https://hdl.handle.net/10356/79248 http://hdl.handle.net/10220/38647 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Nanyang Technological University |
Language: | English |
Similar Items
-
The thrombin-derived host defense peptide GKY25 inhibits endotoxin-induced responses through Interactions with lipopolysaccharide and macrophages/monocytes
by: Schmidtchen, Artur, et al.
Published: (2015) -
A peptide of heparin cofactor II inhibits endotoxin-mediated shock and invasive pseudomonas aeruginosa infection
by: Kalle, Martina, et al.
Published: (2014) -
Thrombin-Derived Host-Defense Peptides Modulate Monocyte/Macrophage Inflammatory Responses to Gram-Negative Bacteria
by: Hansen, Finja C., et al.
Published: (2017) -
An antimicrobial helix A-derived peptide of heparin cofactor II blocks endotoxin responses in vivo
by: Papareddy, Praveen, et al.
Published: (2014) -
Pseudomonas aeruginosa elastase cleaves a C-terminal peptide from human thrombin that inhibits host inflammatory responses
by: van der Plas, Mariena J. A., et al.
Published: (2016)