G-quadruplexes with (4n - 1) guanines in the G-tetrad core : formation of a G-triad·water complex and implication for small-molecule binding

G-quadruplexes are non-canonical structures of nucleic acids, in which guanine bases form planar G-tetrads (G·G·G·G) that stack on each other in the core of the structure. G-quadruplexes generally contain multiple times of four (4n) guanines in the core. Here, we study the structure of G-quadruplexe...

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Main Authors: Heddi, Brahim, Martín-Pintado, Nerea, Serimbetov, Zhalgas, Teuku Mahfuzh Aufar Kari, Phan, Anh Tuan
其他作者: School of Physical and Mathematical Sciences
格式: Article
語言:English
出版: 2018
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在線閱讀:https://hdl.handle.net/10356/88403
http://hdl.handle.net/10220/45778
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機構: Nanyang Technological University
語言: English

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