G-quadruplexes with (4n - 1) guanines in the G-tetrad core : formation of a G-triad·water complex and implication for small-molecule binding
G-quadruplexes are non-canonical structures of nucleic acids, in which guanine bases form planar G-tetrads (G·G·G·G) that stack on each other in the core of the structure. G-quadruplexes generally contain multiple times of four (4n) guanines in the core. Here, we study the structure of G-quadruplexe...
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Main Authors: | Heddi, Brahim, Martín-Pintado, Nerea, Serimbetov, Zhalgas, Teuku Mahfuzh Aufar Kari, Phan, Anh Tuan |
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Other Authors: | School of Physical and Mathematical Sciences |
Format: | Article |
Language: | English |
Published: |
2018
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/88403 http://hdl.handle.net/10220/45778 |
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Institution: | Nanyang Technological University |
Language: | English |
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