Nγ-hydroxyasparagine: a multifunctional unnatural amino acid that is a good P1 substrate of asparaginyl peptide ligases

Nγ-hydroxyasparagine: a multifunctional unnatural amino acid that is a good P1 substrate of asparaginyl peptide ligases

Peptidyl asparaginyl ligases (PALs) are powerful tools for peptide macrocyclization. Herein, we report that a derivative of Asn, namely Nγ -hydroxyasparagine or Asn(OH), is an unnatural P1 substrate of PALs. By Asn(OH)-mediated cyclization, we prepared cyclic peptides as new matrix metalloproteinase...

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書目詳細資料
Main Authors:	Xia, Yiyin, To, Janet, Chan, Ning-Yu, Hu, Side, Liew, Heng Tai, Balamkundu, Seetharamsing, Zhang, Xiaohong, Lescar, Julien, Bhattacharjya, Surajit, Tam, James P., Liu, Chuan-Fa
其他作者:	School of Biological Sciences
格式:	Article
語言:	English
出版:	2022
主題:	Science::Biological sciences Amino Acids Enzymes
在線閱讀:	https://hdl.handle.net/10356/163147
標簽:	添加標簽沒有標簽, 成為第一個標記此記錄!

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