PD-L1 alternative splicing
PD-L1 is an immune checkpoint molecule which is upregulated in some tumors to evade the immune response. Generation of truncated and nonfunctional PD-L1 variants by modulation of alternative splicing presents a novel strategy for cancer treatments. PD-L1 alternative splicing was studied using minige...
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Main Author: | Zhen, Yashu |
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Other Authors: | Francesc Xavier Roca Castella |
Format: | Thesis-Doctor of Philosophy |
Language: | English |
Published: |
Nanyang Technological University
2022
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/156429 |
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Institution: | Nanyang Technological University |
Language: | English |
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