Carbene-catalyzed direct O-functionalization of ketone: atroposelective access to non-C₂-symmetric binaphthyls
Disclosed here is NHC-catalyzed direct intermolecular trapping of the ketone oxygen atom with the acyl azolium intermediate. The overall reaction is a dynamic kinetic resolution process that converts ketone to the corresponding enol ester with well-controlled axial chirality. Our reaction eventually...
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Main Authors: | Mondal, Bivas, Chen, Hang, Maiti, Rakesh, Wang, Hongling, Cai, Hui, Mou, Chengli, Hao, Lin, Chai, Huifang, Chi, Robin Yonggui |
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Other Authors: | School of Chemistry, Chemical Engineering and Biotechnology |
Format: | Article |
Language: | English |
Published: |
2024
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/173356 |
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Institution: | Nanyang Technological University |
Language: | English |
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